As in many areas of surgical pathology, the field of endocrine pathology is rapidly evolving from a purely descriptive discipline into one that is increasingly based on principles of cellular and molecular biology. Advances in our understanding of endocrine tumors over the past 25 years have been nothing short of extraordinary. To name but a few, these advances include the concept of the neuroendocrine system and its associated neoplasms, the roles of oncogenes and tumor-suppressor genes in the pathogenesis of endocrine tumors, and the role of molecular testing methods in the diagnosis of multiple endocrine neoplasia syndromes. In a multiauthored textbook such as this, the challenge for the editor and the authors is to amalgamate all of this information into workable clinical and pathological concepts. Lloyd and his colleagues have largely succeeded in achieving this formidable goal.
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